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The Department of Urology committed to developing research that will translate into more effective treatments for patients with urologic disorders. Recent or ongoing research programs include:
Biodistribution of Dietary Tomato and Soy Phytochemicals in the Human ProstateConsumption of tomato-based products and soy has been correlated with reduced risk for prostate cancer in human epidemiologic studies. But because human diets are complex, proof that these foods can play a role in cancer prevention has required more evidence. Work by OSU researchers – including Steven Clinton, MD, Kamal Pohar, MD, and Robert Bahnson, MD – has ranged from molecular studies using cells grown in the laboratory to animal models for cancers, as well as human studies. These studies demonstrated that soy and tomato products contain many phytochemicals, natural compounds that affect several components of the carcinogenic cascade.Tomato-Soy Drink Tested Against Prostate CancerUsing a $1.27 million federal grant, a team of OSU researchers developed a promising tomato juice containing soy that has been favorably tested for palatability. A new $1.2 million grant from the National Cancer Institute is allowing the OSU team to test this product in men with prostate cancer. The first study will focus on those planning to undergo prostatectomy.MEAL StudyDr. Bahnson and Electra Paskett, PhD, MsPH, professor of public health, are co-chairs of the Men’s Eating and Living (MEAL) study, a pilot trial of diet change among prostate cancer patients.Role of Reactive Oxygen Species in Cavernous Nerve Damage following Radical ProstatectomyKamal Pohar, MD, and Michael Gong, MD, PhD, continue this study, which is supported by a grant from the U.S. Department of Defense. |